FDC's National Day Shipping Arrangements
September 30,2024
Mid-Autumn Festival | FDC wishes you a happy Mid Autumn Festival and family reunion!
September 12,2024
The 6th CMC China Expo will be held on August 15-16, 2024 at the Suzhou International Expo Center! This exhibition is set up in four major venues, B, C, D, and E, with an exhibition area of 36000 square meters. It covers the themes of biopharmaceuticals and synthetic biology, pharmaceutical CMC&innovation&CXO, MAH&CXO&DS, and pharmaceutical industry chain. It carefully designs over 300 professional topics, covering every link from replication to innovation, from project proposal, research and development to commercialization.
August 6,2024
The main reasons for the failure of new drugs in clinical trials are related to unsatisfactory pharmacokinetic characteristics and toxicity issues. Therefore, this article explores the drug like properties of MR3278 through computer ADMET analysis.
As shown in the bioavailability radar chart, the high bioavailability of MR3278 can be attributed to its optimal physicochemical properties. The radar chart contains six key parameters of oral bioavailability: LIPO (lipophilicity), SIZE (molecular size), POLAR (polarity), INSOLU (solubility), INSATU (saturation), and FLEX (flexibility).
July 24,2024
Research has shown that the PI3K δ inhibitor compound CHMFL-PI3KD-317 exhibits good in vivo efficacy against B-cell associated tumors, such as acute myeloid leukemia (AML). This article describes a bioelectronic isosubstitution method for developing novel 2-aminopyridine PI3K δ inhibitors. Through studying the structure-activity relationship and biological evaluation of similar structures, it was determined that compound MR3278 is an effective PI3K δ inhibitor with certain anti proliferative effects on blood cells in vitro.
July 10,2024
From June 19th to 21st, the 22nd CPHI China 2024 was held at the Shanghai New International Expo Center.
This exhibition has expanded to 26 exhibition halls, with a display area of over 210000 square meters. Nearly 3500 companies representing the pioneering innovation force of China's pharmaceutical industry showcased on the same stage, sharing research results and cutting-edge technologies, leading the new direction of the industry in the future, and providing strong support for the industrialization of pharmaceutical innovative products and the internationalization of domestic innovative drugs. Shanghai Yuhan made its debut at this conference and showcased the company's latest innovative research and development achievements.
June 26,2024
May 5th | FDC wishes for a healthy Dragon Boat Festival!
June 7,2024
The 22nd CPHI China 2024 will be held on June 19, 2024 at the Shanghai New International Expo Center. FDC booth is located at E7C82, looking forward to meeting you!
June 3,2024
PI3K is an intracellular phosphatidylinositol kinase associated with products of oncogenes such as Src and RAS. The PI3K signaling pathway is one of the most frequently activated signaling pathways in human cancer, mediating almost 50% of the occurrence of malignant tumors. Research has shown that excessive activity of the PI3K signaling pathway is significantly correlated with tumor progression, increased tumor microvascular density, and enhanced chemotaxis and invasiveness of cancer cells. At present, PI3K has become an important target for the treatment of various malignant tumors, including breast cancer and follicular lymphoma.
May 28,2024
FDC's Labor Day Shipping Arrangements
April 24,2024
